lundi, octobre 26, 2026

Articles de recherche

Articles de recherche

PubMed (145)
Dr Amin Gasmi, PhD
Dr Amin Gasmi, PhDChercheur en nutrition clinique et micronutrition · +230 publications · 3 533 citations (h-index 32)
South African Journal of BotanyOct. 2026
Phytochimie & Composés Bioactifs

A systematic review of Cinnamomum Bioactives in metabolic and inflammatory disorders: integrating species-specific differences, extraction technologies, and clinical translation

Dr Amin Gasmi, Ankita Wal, K K Sharma, Subhashree Sahoo, Israr Ansari, Ajay Kumar, Vivek Dhir, +3 co-auteurs

Publication scientifique évaluée par les pairs signée par Ankita Wal, K K Sharma, Subhashree Sahoo, Israr Ansari, Ajay Kumar, Vivek Dhir, Santosh Karajgi, Abhijeet Dutta, Amin Gasmi, parue dans South African Journal of Botany (2026). DOI:…

Current gene therapySept. 2026
Neuroprotection & Santé Cérébrale

Artificial Intelligence-Driven Gene Delivery Systems in Dementia: A Comprehensive Review of Mechanisms, Tools, and Therapeutic Strategies

Dr Amin Gasmi, Ankita Wal, Manmohan Shukla, Pranay Wal, Saumya Singh, Brijesh Chaurasia, Hanish Singh Jayasingh Chellammal, +1 co-auteurs

INTRODUCTION/OBJECTIVE: The progressive nature of dementia is represented by a reduction in two or more cognitive functions, including language, memory, executive and visuospatial functioning, personality, and behavior. Only symptoms can…

Current computer-aided drug designSept. 2026
Micronutrition, Métabolisme & Immunité

Harnessing the Power of Large Language Models for Drug Discovery: A Systematic Review of Current Applications and Future Directions

Dr Amin Gasmi, Pranay Wal, Manmohan Shukla, Kritika Sachan, Ankita Wal, Hanish Singh Jayasingh Chellammal, Mohit Tiwari, +1 co-auteurs

INTRODUCTION: The demand for inventive approaches to drug discovery has increased due to the rising costs, time, and failure rates in pharmaceutical research. Large Language Models (LLMs), with their sophisticated natural language process…

Pharmacological reportsSept. 2026
Microbiote & Axe Intestin-Cerveau

Gut microbiota as a modulator of HDAC: insights into Alzheimer’s disease treatment

Ekta Verma, Shweta Mishra, Hanish Singh Jayasingh Chellammal, Prasanna Shama Khandige, Dr Amin Gasmi

The human gut microbiota (GMB) has a significant impact on physiological function, including gastrointestinal health, immune regulation, and redox homeostasis. It consists of diverse microorganisms that support digestion, nutrient absorpt…

Current pharmaceutical designAoût 2026
IA Biomédicale & Nanothérapies

Artificial Intelligence-Driven Diagnosis, Prediction, and Management of Polycystic Ovarian Disease (PCOD): A Comprehensive Systematic Review of Machine Learning, Deep Learning, and Emerging Technologies

Dr Amin Gasmi, Ankita Wal, Mekala Moorthy, Rakesh Verma, Ajay Kumar, Ladi Alik Kumar, Rajni Kant Panik, +2 co-auteurs

INTRODUCTION: Polycystic Ovarian Disease (PCOD) is a complicated endocrine-metabolic disorder affecting about one-quarter of women of reproductive age in the world and a major cause of infertility. This disorder is characterised by hypera…

Current Drug TargetsJuil. 2026
IA Biomédicale & Nanothérapies

Nanocarrier-based Drug Delivery Targeting GPCRs: Challenges, Clinical Translation, and Future Prospects for Precision Medicine

Dr Amin Gasmi, Pranay Wal, Jyotsana Dwivedi, Khairunnisa K., Maninder Pal Singh, D Sathisha, K K Sharma, +2 co-auteurs

Introduction: G-protein Coupled Receptors (GPCRs) are the largest family of classical membrane receptors and the most important class of pharmacological targets, playing roles in many physiological and pathological processes. Targeting a…

Current BioinformaticsJuil. 2026
Microbiote & Axe Intestin-Cerveau

A Survey Review of Computational Models and Their Applications in Predicting Drug-Drug Interactions

Devika Tripathi, Ankita Wal, Vivek Kumar Gupta, Nand Kishore Sharma, Parul Srivastava, Dr Amin Gasmi

Introduction: Drug-drug interactions (DDIs) represent a substantial challenge in contemporary pharmacotherapy, especially given polypharmacy, the effects of foods, and the modification of host-microbiota systems on drugs. Although useful,…

Nanomedicine (London, England)Juil. 2026
IA Biomédicale & Nanothérapies

The EPR effect in human tumors: a critical re-evaluation of a nanomedicine dogma and a call for new targeting paradigms

Dr Amin Gasmi, Jyotsana Dwivedi, Ankita Wal, Mohd Seemab, Anuradha Singh, Pranay Wal, Mohit Tiwari, +2 co-auteurs

For almost four decades, the enhanced permeability and retention (EPR) effect has served as the foundation for passive targeting in cancer nanomedicine. While preclinical studies have reported promising nanoparticle accumulation and thera…

Current neurovascular researchJuin 2026
Neuroprotection & Santé Cérébrale

Neuroprotection Through Nature: The Role of Bioactive Phytocompounds in Alzheimer’s and Parkinson’s Disease

Dr Amin Gasmi, Namra Aziz, Pranay Wal, Gagandeep Singh Basra, Pramod Katti, Shashank Chaturvedi, Abida Khan, +2 co-auteurs

INTRODUCTION: Neurodegenerative diseases, notably Alzheimer's Disease (AD) and Parkinson's Disease (PD), represent a significant and growing global health burden, characterized by progressive cognitive and motor dysfunction. Despite advan…

Current neuropharmacologyJuin 2026
Métaux lourds, Toxicologie & Épigénétique

Targeting α-Synuclein Aggregation in Parkinson’s Disease: A Narrative Review of Current Gene Therapy Strategies

Dr Amin Gasmi, Kuldeep Singh, Pranshul Sethi, Divya Jain, Jeetendra Kumar Gupta, Arpan Kumar Tripathi, Sarvesh Rustagi, +3 co-auteurs

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the accumulation of misfolded α-synuclein (α-syn) aggregates, leading to dopaminergic neuronal loss and motor dysfunction. Current pharmacological treat…

Current drug deliveryJuin 2026
IA Biomédicale & Nanothérapies

Innovative Drug Delivery Strategies for Enhanced Treatment of Antimicrobial Resistance

Dr Amin Gasmi, Pranay Wal, Ankita Wal, Ajay Kumar, Hanish Singh Jayasingh Chellammal, Pratap Kumar Patra, Manish R Bhise, +3 co-auteurs

INTRODUCTION: Antimicrobial resistance (AMR) presents a major global health threat, driven by the overuse and misuse of antibiotics. Traditional drug delivery systems face significant limitations in effectively addressing this issue, incl…

Discover nanoJuin 2026
IA Biomédicale & Nanothérapies

Stimuli-responsive nanogels as intelligent nanocarriers for tumor microenvironment-triggered anticancer drug delivery

Dr Amin Gasmi, Ankita Wal, Sarad Pawar Naik Bukke, Nithin Vidiyala, Shahid Jamil, Krishana Kumar Sharma, Abida Khan, +3 co-auteurs

Stimuli-responsive nanogels have been utilized as perfect nanocarriers for anticancer drug delivery because of their on-demand, controlled, and site-specific drug-releasing chemistry. These HNP are cross-linked hydrophilic polymer nanopar…

Molecular neurobiologyJuin 2026
Neuroprotection & Santé Cérébrale

A Age Related Vascular Senescence: Mystery of Blood-brain Barrier Dysfunction in Neurodegeneration

Dr Amin Gasmi, Tapan Behl, Karthikeyan Jayabalan, Suhas Ballal, Samir Sahoo, Hanish Singh Jayasingh Chellammal, Monica Gulati, +3 co-auteurs

The pathophysiology of neurodegenerative illnesses is increasingly understood to be influenced by vascular aging, with blood-brain barrier (BBB) disruption emerging as a crucial mechanistic connection. Comprising endothelial cells, pericy…

Frontiers in epigenetics and epigenomicsMai 2026
Métaux lourds, Toxicologie & Épigénétique

Environmental epigenetic modifiers in neurodegenerative diseases: a systematic review of epigenomic mechanisms and therapeutic targets

Dr Amin Gasmi, Pranay Wal, Sunita Mishra, Debashish Pradhan, Ankita Wal, Debashis Purohit, Lalit Mohan Nainwal, +2 co-auteurs

BACKGROUND: Environmental contaminants and neurotoxicants are becoming more widely acknowledged as major causes of neurodegenerative illnesses due to systemic biological disruption including oxidative stress, mitochondrial dysfunction, ch…

Current topics in medicinal chemistryMai 2026
Phytochimie & Composés Bioactifs

Exploring the Ethnopharmacology, Phytochemistry, Geographic Distribution, and Pharmacological Properties of the Genus Mangifera

Dr Amin Gasmi, Zulfa Nooreen, S Renuka Jyothi, Poonam Jaisal, Mamata Chahar, K N V Chenchu Lakshmi, Anup Patil, +1 co-auteurs

The genus Mangifera (Anacardiaceae) is widely distributed across most tropical and subtropical regions and has long been used in traditional medicine for its nutritional value and for treating aging-related conditions, parasitic infection…

Computational biology and chemistryOct. 2026
Métaux lourds, Toxicologie & Épigénétique

Advances in artificial intelligence for predictive toxicology: From QSAR and omics integration to clinical safety translation

Dr Amin Gasmi, Pranay Wal, Jyotsana Dwivedi, Kanika Pandey, Krishana Kumar Sharma, Mohit Tiwari, Md Sajid Ali, +2 co-auteurs

The benefit of predictive toxicology strategies utilized in drug discovery to predict possible early-stage side effects. Common methods can be performed in vitro or in vivo and are lengthy, expensive, and often poorly correlated with huma…

Current neurovascular researchMai 2026
Neuroprotection & Santé Cérébrale

Traditional Chinese Medicine in the Modern Era; Network Pharmacology Exploration of Neuroprotective Mechanisms: A Systematic Review

Dr Amin Gasmi, Pranay Wal, Namra Aziz, Sakshi Srivastava, Ankita Wal, Abida Khan, V Vijayanandhan, +2 co-auteurs

INTRODUCTION: Alzheimer's Disease (AD) is a multifactorial neurodegenerative disorder characterized by complex molecular dysregulation that cannot be adequately addressed by single-- target therapeutic strategies. Traditional Chinese Medi…

Current drug targetsMai 2026
Métaux lourds, Toxicologie & Épigénétique

Decoding the Molecular Targets of Luteolin and Fisetin: Emerging Trends in Flavonoid-Based Therapeutics (A Systematic Review)

Dr Amin Gasmi, Namra Aziz, Ankita Wal, Gazala Parveen, Gagandeep Singh Basra, Roshni Tandey, Abida Khan, +2 co-auteurs

BACKGROUND: Luteolin and fisetin are emerging lead flavonoids with significant therapeutic promise due to their wide-spectrum modulation of key molecular signalling pathways implicated in oxidative stress, inflammation, metabolic dysfunct…

Current neuropharmacologyMai 2026
Métaux lourds, Toxicologie & Épigénétique

Exploring Mitochondrial Dysfunction and Protective Therapeutic Approaches to Counteract Its Role in Alzheimer’s Disease Progression

Dr Amin Gasmi, Sanjana Gupta, P Mohamed Nihal, Talha Jawaid, Astik Manju Ashesh, Manish R Bhise, Manoj Rawat, +5 co-auteurs

Alzheimer's disease (AD) is the primary cause of dementia, characterized by a progres-sive decrease in mental abilities and the accumulation of amyloid-beta (Aβ) peptides in the brain. The combination of these peptides leads to the develo…

Current drug targetsMai 2026
Micronutrition, Métabolisme & Immunité

Target-based Antidiabetic Indole Derivatives and Insights into Structure-activity Relationships: A Mechanistic Update 2020-2025

Dr Amin Gasmi, Ankita Wal, Pranay Wal, Akanksha Gupta, G Hemalatha, Mohit Kumar, Hanish Singh Jayasingh Chellammal, +2 co-auteurs

INTRODUCTION: Type 2 diabetes mellitus (T2DM) continues to rise globally, and the limitations of existing therapies highlight the urgent need for novel interventions. Indole derivatives have emerged as promising candidates due to their st…

Current Respiratory Medicine ReviewsMai 2026
Métaux lourds, Toxicologie & Épigénétique

Unraveling Pulmonary Inflammation: From Cytokines to Herbal Therapeutics

Dr Amin Gasmi, Ankita Wal, Harshit Prajapati, Zulfa Nooreen, Vijay Kumar, Sanjay Nagdev, Abdul Rahamanulla, +2 co-auteurs

Background: Pulmonary inflammation is a prevalent and treatable respiratory disorder, often associated with chronic obstructive pulmonary disease (COPD), emphysema, and chronic bronchitis. It arises due to exposure to harmful gases, cigar…

Current pharmacogenomics and personalized medicineMai 2026
IA Biomédicale & Nanothérapies

AI-Enabled Personalized Medicine in Lung Cancer: Diagnostics, Prognostics, and Targeted Drug Delivery- A Systematic Review

Zulfa Nooreen, Rohini Armo, Harsh Vardhan Johri, Ramenani Hari Babu, Parveen Nehra, Dr Amin Gasmi

Introduction: With mutations in important proto-oncogenic drivers such as Kirsten rat sarcoma and epidermal growth factor receptor, non-small cell lung cancer has a diverse genetic background. Regardless of smoking history, Kras-activatin…

Current cardiology reviewsAvr. 2026
Micronutrition, Métabolisme & Immunité

A Narrative Review on Repurposing Azithromycin for Rheumatic Heart Disease: Exploring its Therapeutic Potential and Mechanisms of Action

Dr Amin Gasmi, Pranay Wal, Ankita Wal, Ajay Kumar, Rakesh Verma, Anurag Rawat, Hanish Singh Jayasingh Chellammal, +3 co-auteurs

INTRODUCTION: Despite effective preventative measures, rheumatic heart disease (RHD) continues to be a significant contributor to cardiovascular morbidity and mortality in low- and middle- income nations. Azithromycin (AZM) has drawn atte…

Current Drug Research ReviewsAvr. 2026
Neuroprotection & Santé Cérébrale

Diabetic Neuropathy: Recent Diagnostic Advancements and Emerging Multimodal Therapeutic Strategies

Dr Amin Gasmi, Rama Rao Nadendla, Shubham Rathour, Pranay Wal, Ankita Wal, Madhuri Baghel, Vijay Kumar, +2 co-auteurs

Abstract: Diabetic Neuropathy (DN) is among the most prevalent and debilitating microvascular complications of diabetes mellitus, with Distal Symmetric Polyneuropathy (DPN) representing the predominant phenotype. Despite decades of resear…

Current hypertension reviewsMars 2026
Micronutrition, Métabolisme & Immunité

Exploring Non-pharmacological Hypertension Management: DASH, Paleolithic, and Ketogenic Diet Comparisons: A Systematic Review

Dr Amin Gasmi, Pranay Wal, Deepankar Rath, Neha Verma, Ankita Wal, Pallishree Bhukta, Arin Natania, +3 co-auteurs

INTRODUCTION: Hypertension impacts over one-third of the global population of adults and is a significant contributor to premature mortality, despite substantial progress in pharmaceutical interventions. Increasing evidence supports dieta…

Current Signal Transduction TherapyMars 2026
Neuroprotection & Santé Cérébrale

Integrative Therapeutic Strategies for Diabetes-induced Cognitive Decline (DCI): Role of Mechanistic Targets and Nutritional Modulation

Dr Amin Gasmi, Pranay Wal, Poorvi Grover, A. Mohathasim Billah, Abida, Chethan IA, Muhammed Ameen MP, +2 co-auteurs

Introduction: Diabetes-induced cognitive impairment (DCI) has emerged as a significant yet underexplored complication of diabetes mellitus. Despite its growing prevalence, effective strategies for the prevention and management of DCI rema…

Current Organic ChemistryMars 2026
Neuroprotection & Santé Cérébrale

Phytochemical Composition and Mechanistic Pharmacology of the Citrus Genus: Focus on Organic Constituents

Dr Amin Gasmi, Himangi Vig, Ankita Wal, Preeti Sharma, Jyotsana Dwivedi, Bhagawati Saxena, Nardev Singh, +3 co-auteurs

The Citrus genus, which includes species such as Citrus medica, Citrus sinensis, Citrus paradisi, Citrus aurantiifolia, Citrus limon, and Citrus reticulata, is a wellrecognized source of diverse bioactive compounds with broad pharmacologi…

Current neuropharmacologyMars 2026
Neuroprotection & Santé Cérébrale

The Role of Non-Pharmacological Interventions in Attenuating Anxiety and Stress Symptoms in PTSD: A Systematic Review

Dr Amin Gasmi, Ankita Wal, Hanish Singh Jayasingh Chellammal, Rakesh Verma, Himangi Vig, Shraddha Mishra, Pranay Wal, +3 co-auteurs

INTRODUCTION/OBJECTIVE: Pharmacological treatments for Post-Traumatic Stress Disorder (PTSD), a disorder that affects emotions and mental health and is thought to be therapeutically deficient, either appear to have a number of adverse eff…

Current Organic ChemistryMars 2026
Phytochimie & Composés Bioactifs

Therapeutic Advances of Phytochemicals and Clinical Trials in Renal Cell Carcinoma: Evidence from 2019-2025

Dr Amin Gasmi, Zulfa Nooreen, Ankita Wal, Alka Kurmi, Priyanka Gupta, Roshni Tandey, Abida Khan, +1 co-auteurs

abstract: More than 90% of all renal malignancies are renal cell carcinoma, the most prevalent kind of kidney cancer, and possess a diverse set of illnesses that can be hereditary or sporadic. Approximately 14,000 individuals pass away fr…

Current Organic ChemistryMars 2026
Phytochimie & Composés Bioactifs

Pharmacological Efficacy and Traditional Uses of Cannabis sativa: A Comprehensive Review

Dr Amin Gasmi, Ankita Wal, Shweta Yadav, Kamal Deka, Bhagawati Saxena, Namra Aziz, Nardev Singh, +2 co-auteurs

Cannabis sativa is a chemically diverse plant species that has attracted significant attention due to its rich profile of secondary metabolites, particularly cannabinoids. It is a rich source of bioactive compounds, particularly cannabino…

Current medicinal chemistryMars 2026
Phytochimie & Composés Bioactifs

Broccoli and Other Botanicals in the Prevention and Treatment of Premenstrual Syndrome

Dr Amin Gasmi, Sadaf Noor, Salva Piscopo, Asma Gasmi Benahmed, Alain Menzel, Mariia Shanaida, +6 co-auteurs

Pre-menstrual syndrome (PMS) consists of a range of physical, mental, and behavioral changes that can affect women at various stages during their menstrual cycle. These changes are caused by fluctuations in hormone levels, which play a si…

Current topics in medicinal chemistryFévr. 2026
Neuroprotection & Santé Cérébrale

Antibody Therapies Targeting Amyloid-β and Tau in Alzheimer’s Disease with Insights on Mechanisms, Clinical Trials, and Challenges

Dr Amin Gasmi, Astik Manju Ashesh, Sanjana Gupta, Talha Jawaid, Pranay Wal, Manish R Bhise, Ajay Kumar, +1 co-auteurs

Alzheimer's Disease (AD) is characterized by amyloid-β (Aβ) deposits and neurofibrillary tangles containing phosphorylated tau protein. Around 57 million people worldwide were estimated by the World Health Organization to have dementia in…

BiogerontologyFévr. 2026
Neuroprotection & Santé Cérébrale

Synaptic aging and neurodegeneration: the role of synaptic vesicle dynamics and neurotransmitter imbalance

Dr Amin Gasmi, Pranay Wal, Abhijit Dutta, Talha Jawaid, Mujeeb Ur Rahman, Gowri Krishnaperumal, S Renuka Jyothi, +9 co-auteurs

Synaptic aging is a core manifestation of brain aging arising from the convergence of fundamental biological aging processes, including genomic instability, loss of proteostasis, mitochondrial dysfunction, oxidative stress, and chronic lo…

Journal of Molecular LiquidsJanv. 2026
Micronutrition, Métabolisme & Immunité

Exploring the effect of extremolytes on thermal and colloidal stability of bovine serum albumin

Dr Amin Gasmi, Anasuya Patil, Tanu Rawal, Akhtar Rasool, Atul Singh, Omar Awad Alsaidan, Sami Ibrahim Alzarea, +6 co-auteurs

Publication scientifique évaluée par les pairs signée par Anasuya Patil, Tanu Rawal, Akhtar Rasool, Atul Singh, Omar Awad Alsaidan, Sami Ibrahim Alzarea, Chandan Mukherjee, Juhikaben Vaibhavkumar Patel, Debashis Purohit, Shiv Bahadur, Raj…

Computational biology and chemistryAvr. 2026
IA Biomédicale & Nanothérapies

From 16S rRNA to deep learning: Evolution of computational approaches in human microbiome studies

Jyotsana Dwivedi, Man Mohan Shukla, Akanksha Upadhyay, Ankita Wal, Krishana Kumar Sharma, Dr Amin Gasmi

The human microbiome plays a vital role in maintaining physiological balance and influencing immunity, metabolism, and disease development. Over the past decade, the field has witnessed a remarkable transition from traditional 16S rRNA se…

Pakistan Journal of Medical & Cardiological ReviewDéc. 2025
Neuroprotection & Santé Cérébrale

PSYCHOLOGICAL CONSEQUENCES OF DIABETES MELLITUS ON PATIENTS’ EMOTIONAL WELL-BEING AND DAILY LIFE ADJUSTMENTS

Dr Amin Gasmi, Mudassar Khan, Syed Zahoor Ul Hassan Zaidi, Amna Iram, Muhammad Mudassar, Amjad Hussain, Dr. Muhammad Zeeshan Ali, +9 co-auteurs

An individual's physical, social, emotional, and psychological well-being can be impacted by diabetes, a chronic metabolic disease.Diabetes patients frequently face psychological difficulties that, if left untreated, have a significant de…

Advances in experimental medicine and biologyJanv. 2026
Micronutrition, Métabolisme & Immunité

Innovative Biomarkers for Oral Immunity: Advancements and Clinical Applications

Dr Amin Gasmi, Asma Gasmi Benahmed, Amine Nehaoua, Sadaf Noor, Alain Menzel

Oral immunity is an essential barrier for protection against pathogens, supporting oral health, and overall health-related challenges. Nevertheless, dysregulation of oral immunity results in different pathological conditions that are ofte…

Advances in experimental medicine and biologyJanv. 2026
Microbiote & Axe Intestin-Cerveau

Diabesity and Oral Immunity: Exploring the Interconnection

Amine Nehaoua, Dr Amin Gasmi, Sadaf Noor, Asma Gasmi Benahmed

Diabesity-obesity and type 2 diabetes mellitus (T2DM)-has a profound effect on oral health, and modulation of the oral immune system may help in managing it. This review aims to elucidate the complex interconnection between diabesity, ora…

Advances in experimental medicine and biologyJanv. 2026
Microbiote & Axe Intestin-Cerveau

The Oral Microbiome, Oral Hyperpermeability, and Periodontitis in Metabolic Syndrome

Amine Nehaoua, Dr Amin Gasmi, Sadaf Noor, Asma Gasmi Benahmed

The links between the oral microbiome, oral hyperpermeability, periodontitis, and metabolic syndrome (MetS) are good examples of the oral-systemic health connection. The oral microbiota is involved in host defense and metabolism. Oral dys…

Molecular nutrition & food researchDéc. 2025
Microbiote & Axe Intestin-Cerveau

Gut Microbiota and Dietary Strategies for Age-Related Diseases

Dr Amin Gasmi, Prabhat Upadhyay, Sudhir Kumar, Hanish Singh Jayasingh Chellammal, Neha Sahu, Shivani Srivastava, Raj Kumar, +1 co-auteurs

The gut microbiota plays a vital role in the aging process and the onset of age-related diseases, offering promising targets for dietary interventions to support healthy aging. This diverse microbial community influences metabolism, immun…

Letters in Drug Design & DiscoveryNov. 2025
Métaux lourds, Toxicologie & Épigénétique

Emerging DNA- and RNA-based therapeutic strategies in hepatocellular carcinoma: A molecular approach to precision medicine

Dr Amin Gasmi, Zulfa Nooreen, Ankita Wal, Anjali Shukla, A. Venkata Badarinath, Nishant Kumar, Tanmay Sarma, +2 co-auteurs

Hepatocellular carcinoma (HCC) is the most common sole malignancy of the liver as well as one of the leading causes of cancer-related death throughout the globe. Current epidemiological surveys note a distinct shift in the causes of HCC a…

Cardiovascular & hematological disorders drug targetsJanv. 2026
Métaux lourds, Toxicologie & Épigénétique

Therapeutic Targets for Myocardial Fibrosis: A Comprehensive Review of Current and Emerging Approaches

Dr Amin Gasmi, Ankita Wal, Anurag Rawat, Rakesh Verma, Azhar Rasheed, Uttam Prasad Panigrahy, Anwesha Das, +1 co-auteurs

INTRODUCTION: Cardiovascular disorders (CVDs) remain the leading cause of global mortality, surpassing other chronic illnesses. An alarming rise in CVD-related deaths, particularly among younger populations, has intensified research effor…

Current gene therapyAoût 2025
Micronutrition, Métabolisme & Immunité

Tailored Therapies for Hereditary Diabetes: Unraveling the Genetic Underpinnings of MODY and Neonatal Diabetes

Dr Amin Gasmi, Jyotsana Dwivedi, Shubhi Kaushal, Pranay Wal, Deependra Pratap Singh, Priyanka Gupta, Pulipati Sowjanya, +2 co-auteurs

INTRODUCTION: Hereditary forms of diabetes, including Maturity-Onset Diabetes of the Young (MODY) and Neonatal Diabetes Mellitus (NDM), are rare monogenic disorders caused by mutations in genes involved in pancreatic development, beta-cel…

South African Journal of BotanyAoût 2025
Micronutrition, Métabolisme & Immunité

Unveiling the chemical composition, bioactive properties, and potential applications of fennel essential oil

Ankita Wal, Divyanshi Gupta, Dr Amin Gasmi, Abida Kalsoom Khan, Astik Manju Ashesh, Ajay Kumar V, +1 co-auteurs

Publication scientifique évaluée par les pairs signée par Ankita Wal, Divyanshi Gupta, Amin Gasmi, Abida Kalsoom Khan, Astik Manju Ashesh, Ajay Kumar V, Dileep Kumar, parue dans South African Journal of Botany (2025). DOI:10.1016/j.sajb.2…

Current protein & peptide scienceAoût 2025
Phytochimie & Composés Bioactifs

Pharmacological Evaluation of the Combination Therapy of Novel Herbal Mixture in Polycystic Ovary Syndrome

Dr Amin Gasmi, Chandana Pyne, Chandra Shekhar Barik, Rakesh Verma, Rajendra Dnyandeo Dighe, Namra Aziz, Mohd Imran, +2 co-auteurs

INTRODUCTION: An endocrine condition known as Poly-Cystic Ovarian Syndrome (PCOS) makes females of reproductive age more susceptible to insulin resistance, excessive levels of male hormones, and delayed ovulation. It is the main reason th…

Central nervous system agents in medicinal chemistryJuil. 2025
Neuroprotection & Santé Cérébrale

Role of Morin & Alpha-Lipoic Acid in Diabetic Neuropathic Pain

Dr Amin Gasmi, Ankita Wal, Pranay Wal, Gagandeep Singh Basra, Ritu Rani Yadav, Srilekha Das Nag, Shiva Mishra, +1 co-auteurs

Recent studies have shown that plant-derived flavonoids may be useful in the treatment of diabetes. Plants in the Moraceae family are commonly known to contain the bioflavonoid morin. Its pharmacological properties include anti-inflammato…

International ophthalmologyMai 2025
Phytochimie & Composés Bioactifs

Molecular pathway and mechanism responsible for the progress of thyroid-associated orbitopathy

Jyotsana Dwivedi, Shubhi Kaushal, Poonam Arora, Pranay Wal, Ankita Wal, Dr Amin Gasmi

PURPOSE: Our study aims to summarize the current knowledge concerning the molecular pathway and mechanism responsible for the progress of orbitopathy in the thyroid. METHOD: A thorough investigation of the literature was conducted using S…

Current Signal Transduction TherapyMai 2025
Micronutrition, Métabolisme & Immunité

The Therapeutic Potential of TGF-β as a Target for Multiple Chronic Diseases: A Comprehensive Review of Pharmacologically Approved Drugs and Investigational Agents

Dr Amin Gasmi, Ankita Wal, Azhar Rasheed, Pranay Wal, Manish Ramesh Bhise, Manisha Parmar, Deepak Nathiya, +2 co-auteurs

Background: Noncommunicable chronic diseases account for the highest number of mortalities across the globe and are responsible as the greatest contributor to medical healthcare expenses. To create new medicines to fight these diseases, w…

Current drug research reviewsJanv. 2026
Micronutrition, Métabolisme & Immunité

Diabetic Wound Healing: Mechanism and Treatment Strategies with a Special Focus on Angiogenesis

Dr Amin Gasmi, Ankita Wal, Nidhi Singh, Pranay Wal, Rakesh Verma, S Gowrish, Rahul Subhash Buchade, +2 co-auteurs

Due to the numerous comorbidities associated with diabetes mellitus (DM), its complications of poor wound healing, persistent ulceration, and subsequent limb amputation, DM is becoming a major global health concern. The need for research…

Current medicinal chemistryAvr. 2025
Phytochimie & Composés Bioactifs

Anti-cancer Properties of Epigallocatechin-3-gallate (EGCG) and its Signaling Pathways

Dr Amin Gasmi, Alain Menzel, Asma Gasmi Benahmed, Kateryna Uminska, Olha Mykhailenko, Victoriya Georgiyants, +3 co-auteurs

Green tea is a traditional drink found in Asian countries, made up of four derivatives. One of the derivatives is epigallocatechin-3-gallate (EGCG). EGCG provides therapeutic benefits for cancer, heart disease, diabetes, and obesity. Howe…

Current drug metabolismAvr. 2025
Micronutrition, Métabolisme & Immunité

A Data Mining Approach on Polypharmacy and Drug-drug Interactions of Common Diabetes Medications

Dr Amin Gasmi, Jyotsana Dwivedi, Shubhi Kaushal, Pranay Wal, Darshan Jogi Chandrashekhar, Ankita Sharma, Deepak Nathiya, +1 co-auteurs

BACKGROUND: When managing diabetes, polypharmacy the use of several drugs simultaneously to obtain the best possible glucose control is typical. Drug-drug interactions (DDIs), which can result in side effects and reduced treatment efficac…

NeuroscienceAvr. 2025
Métaux lourds, Toxicologie & Épigénétique

Artificial intelligence in stroke rehabilitation: From acute care to long-term recovery

Dr Amin Gasmi, Spandana Rajendra Kopalli, Madhu Shukla, B Jayaprakash, Mayank Kundlas, Ankur Srivastava, Jayant Jagtap, +7 co-auteurs

Stroke is a leading cause of disability worldwide, driving the need for advanced rehabilitation strategies. The integration of Artificial Intelligence (AI) into stroke rehabilitation presents significant advancements across the continuum…

Current pharmaceutical designFévr. 2025
Micronutrition, Métabolisme & Immunité

Recent Advancement in Drug Targeting Therapies in the Treatment of Pancreatic Cancer

Ranjit K Harwansh, Junainah Abd Hamid, Pranay Wal, Rohitas Deshmukh, Pratap Kumar Patra, Dr Amin Gasmi

OBJECTIVE OF THE STUDY: This review aims to critically analyze the scope for targeting drugs towards the treatment of improving outcomes in PDAC, focusing on DNA repair inhibitors, antiangiogenic therapy, inhibitors of the KRAS pathway, a…

Current drug targetsFévr. 2025
Micronutrition, Métabolisme & Immunité

Unfurling the Potential of Antiviral Agents Aimed for RNA Virus Ailment

Dr Amin Gasmi, Ritchu Babbar, Jasmeen Kaur, Kajalpreet Kaur, Swikriti, Vijay Dhondiram Vagh, Monika Sachdeva, +3 co-auteurs

Globally, high mortality is brought on by RNA viruses, which are linked to chronic human disorders. Viruses dominate the WHO's current ranking of the top 10 global health hazards, especially RNA viruses. RNA viruses, like HIV, SARS-CoV-2,…

NeuroscienceMars 2025
Neuroprotection & Santé Cérébrale

Synaptic plasticity and neuroprotection: The molecular impact of flavonoids on neurodegenerative disease progression

Dr Amin Gasmi, Spandana Rajendra Kopalli, Tapan Behl, Ashishkumar Kyada, M M Rekha, Mayank Kundlas, Pooja Rani, +9 co-auteurs

Flavonoids are a broad family of polyphenolic chemicals that are present in a wide variety of fruits, vegetables, and medicinal plants. Because of their neuroprotective qualities, flavonoids have attracted a lot of interest. The potential…

Current medicinal chemistryFévr. 2025
Métaux lourds, Toxicologie & Épigénétique

Lipid Biochemistry and its Role in Human Diseases

Amine Nehaoua, Dr Amin Gasmi, Asma Gasmi Benahmed, Sadaf Noor, Geir Bjørklund

Lipids play a variety of roles in living systems. They are a source of extremely high energy and a part of almost all signaling and biological processes. Despite the liver being the hub of lipid metabolism, lipid metabolism occurs across…

Current Chemical BiologyFévr. 2025
Neuroprotection & Santé Cérébrale

Novel Delivery Approaches and Therapeutic Potential of Resveratrol – A Review

Zulfa Nooreen, Awani Kumar Rai, Pranay Wal, Manish Ramesh Bhise, Jadhav Balaji, Dr Amin Gasmi

Resveratrol (RV) is a well-known polyphenolic compound found in many different plants, including the fruits of grape, peanut, and berry trees. It is well-known for its links to a number of health benefits, including those related to gluco…

Current cardiology reviewsJanv. 2025
Métaux lourds, Toxicologie & Épigénétique

Evaluation of the Effect of Virgin Rice Bran Oil (VRBO) on DoxorubicinInduced Cardiotoxicity in Wistar Rats

Dr Amin Gasmi, Suseela Prema, Rakesh Verma, Amritesh Nagarwal, Meenakshi Bharkatiya, Madhuri Baghel, Ladli Kishore, +2 co-auteurs

OBJECTIVE: The usage of doxorubicin (DOX), an antineoplastic drug that is frequently used for the cure of cancer, is restricted to maximal doses due to its cardiac toxicity. Reactive oxygen species produced by DOX result in lipid peroxida…

Current protein & peptide scienceJanv. 2025
Neuroprotection & Santé Cérébrale

The Role of Sirtuins in Diabetic Nephropathy: A Comprehensive Review

Dr Amin Gasmi, Pranay Wal, Tarannum Tarannum, Lalji Baldaniya, Kiranjeet Kaur, Priyanka Singh, Namra Aziz, +2 co-auteurs

INTRODUCTION: Diabetic nephropathy is characterized by elevated oxidative stress and chronic inflammation in the kidneys. A class of proteins called sirtuins is well-known to be important for a number of cellular functions, such as metabo…

Reproductive sciences (Thousand Oaks, Calif.)Janv. 2025
Neuroprotection & Santé Cérébrale

Unveiling the Neurotransmitter Symphony: Dynamic Shifts in Neurotransmitter Levels during Menstruation

Dr Amin Gasmi, Mayur B Kale, Nitu L Wankhede, Barkha K Goyanka, Reena Gupta, Ashok Kumar Bishoyi, Deepak Nathiya, +9 co-auteurs

The menstrual cycle is an intricate biological process governed by hormonal changes that affect different facets of a woman's reproductive system. This review provides an overview of neurotransmitter alterations during different menstrual…

Letters in Drug Design & DiscoveryNov. 2024
Phytochimie & Composés Bioactifs

A Systemic Review on Phytochemicals and Novel Approaches for the Management of Hepatic Cancer

Zulfa Nooreen, Fariha Sumayya, Pranay Wal, Chirag Goda, Mohd Imran, Dr Amin Gasmi

Publication scientifique évaluée par les pairs signée par Zulfa Nooreen, Fariha Sumayya, Pranay Wal, Chirag Goda, Mohd Imran, Amin Gasmi, parue dans Letters in Drug Design & Discovery (2024). DOI:10.2174/0115701808334721241111073635

Ageing research reviewsDéc. 2024
Métaux lourds, Toxicologie & Épigénétique

Epigenetic Biomarkers in Alzheimer’s Disease: Diagnostic and Prognostic Relevance

Dr Amin Gasmi, Tapan Behl, Ashishkumar Kyada, R Roopashree, Deepak Nathiya, Renu Arya, M Ravi Kumar, +8 co-auteurs

Alzheimer's disease (AD) is a leading cause of cognitive decline in the aging population, presenting a critical need for early diagnosis and effective prognostic tools. Epigenetic modifications, including DNA methylation, histone modifica…

International Peer-Reviewed JournalOct. 2024
Micronutrition, Métabolisme & Immunité

Le Magnésium et le Potassium : Des Alliés contre le Cholestérol et la Qualité de Vie pour les Patients Diabétiques de Type 2 ?

Dr Amin Gasmi, et al.

Les études précédentes sur la relation entre l'apport alimentaire en potassium et en magnésium et le risque de diabète de type 2 (T2D) ont donné des résultats contradictoires. C'est pourquoi une équipe de chercheurs a décidé de mener une…

Current medicinal chemistryJanv. 2024
Microbiote & Axe Intestin-Cerveau

Periodontitis Continuum: Antecedents, Triggers, Mediators, and Treatment Strategies

Asma Gasmi Benahmed, Torsak Tippairote, Dr Amin Gasmi, Sadaf Noor, Oleksandr Avdeev, Yurii Shanaida, +4 co-auteurs

Periodontitis (PD) is a chronic inflammatory disease of the periodontium characterized by the formation of gingival pockets and gingival recession. The local inflammatory environment can lead to the destruction of the extracellular matrix…

Current Organic ChemistrySept. 2024
Phytochimie & Composés Bioactifs

An Insight into Ethanopharmacology, Phytochemistry, and Pharmacological Properties of Genus Andrographis

Dr Amin Gasmi, Zulfa Nooreen, Sangappa Teli, Parul Srivastava, Biswajit Dash, Ankita Wal, Mohd Imran, +1 co-auteurs

Andrographis is a member of the family Acantheceae. It contains approximately 44 accepted species. Among them, Andrographis paniculata has been extensively studied during the last decade. The genus contains triterpenoids as the main class…

Ageing research reviewsAoût 2024
Métaux lourds, Toxicologie & Épigénétique

The Link Between Alzheimer’s Disease and Stroke: A Detrimental Synergism

Dr Amin Gasmi, Tapan Behl, Ishnoor Kaur, Aayush Sehgal, Prasanna Shama Khandige, Mohd Imran, Monica Gulati, +5 co-auteurs

Being age-related disorders, both Alzheimer's disease (AD) and stroke share multiple risk factors, such as hypertension, smoking, diabetes, and apolipoprotein E (APOE) Ɛ4 genotype, and coexist in patients. Accumulation of amyloid-β plaque…

International Peer-Reviewed JournalJuin 2024
Micronutrition, Métabolisme & Immunité

L’Eczéma et le Sodium : Un Risque Accru pour les Patients

Dr Amin Gasmi, et al.

L'Eczéma et le Sodium : Un Risque Accru pour les PatientsL'alimentation riche en sodium pourrait augmenter le risque d'eczéma, selon des chercheurs de l'Université de Californie à San Francisco (UCSF). Ils ont découvert que consommer seul…

Current medicinal chemistryJanv. 2025
Métaux lourds, Toxicologie & Épigénétique

Optimizing the Antimicrobial Effects by using Natural Compounds in COVID-19 Management

Dr Amin Gasmi, Asma Gasmi Benahmed, Maryam Dadar, Pavan Mujawdiya, Geir Bjorklund

COVID-19 has emerged as the most significant global health issue of our time. The causative agent, SARS-CoV-2, causes extensive damage to the lower respiratory tract in susceptible populations, leading to lung damage and death. COVID-19-i…

Current medicinal chemistryJanv. 2025
Microbiote & Axe Intestin-Cerveau

Hallmarks of Periodontitis

Asma Gasmi Benahmed, Dr Amin Gasmi, Sadaf Noor, Yuliya Semenova, Alireza Emadali, Maryam Dadar, +3 co-auteurs

Periodontitis is a complex polymicrobial disease of the oral cavity that affects tooth-supporting tissues. It is caused by multiple factors, such as pathogenic bacteria, genetic predisposition, and host immune response factors. The pathog…

Current pharmaceutical designAvr. 2024
Micronutrition, Métabolisme & Immunité

Ayurvedic and Chinese Herbs against Coronaviruses

Dr Amin Gasmi, Sonia Kanwal, Petro Oliinyk, Roman Lysiuk, Mariia Shanaida, Asma Gasmi Benahmed, +7 co-auteurs

COVID-19 is a viral disease that infects the lower airways, causing severe acute respiratory syndrome (SARS) and fatal pneumonia. The ripple effect of the COVID-19 outbreak has created serious problems in the healthcare systems of many co…

Current pharmaceutical designMars 2024
Micronutrition, Métabolisme & Immunité

The Role of Traditional Chinese Medicine and Chinese Pharmacopoeia in the Evaluation and Treatment of COVID-19

Dr Amin Gasmi, Sadaf Noor, Maryam Dadar, Yuliya Semenova, Alain Menzel, Asma Gasmi Benahmed, +1 co-auteurs

The epidemic prompted by COVID-19 continues to spread, causing a great risk to the general population's safety and health. There are still no drugs capable of curing it. Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory…

Current medicinal chemistryJanv. 2025
Neuroprotection & Santé Cérébrale

Herbal Treatments for Obesity: A Review

Dr Amin Gasmi, Sadaf Noor, Pavan Kumar Mujawdiya, Muhammad Akram, Aisha Manzoor, Geir Bjorklund

Obesity is the most pervasive metabolic disorder, further linked with many other diseases, including diabetes, hypertension, cardiovascular disorders, and sleep apnea. To control the increasing weight of obese individuals, experts usually…

Current medicinal chemistryJanv. 2025
Métaux lourds, Toxicologie & Épigénétique

Genetic and Epigenetic Determinants of COVID-19 Susceptibility: A Systematic Review

Dr Amin Gasmi, Laura Kassym, Alain Menzel, Wajiha Anzar, Maryam Dadar, Yuliya Semenova, +6 co-auteurs

BACKGROUND: The molecular mechanisms regulating coronavirus pathogenesis are complex, including virus-host interactions associated with replication and innate immune control. However, some genetic and epigenetic conditions associated with…

Current medicinal chemistryJanv. 2025
Micronutrition, Métabolisme & Immunité

The Possible Roles of β-alanine and L-carnosine in Anti-aging

Dr Amin Gasmi, Pavan Kumar Mujawdiya, Roman Lysiuk, Mariia Shanaida, Massimiliano Peana, Salva Piscopo, +6 co-auteurs

alanine (BA), being a non-proteinogenic amino acid, is an important constituent of L-carnosine (LC), which is necessary for maintaining the muscle buffering capacity and preventing a loss of muscle mass associated with aging effects. BA i…

Elsevier eBooksJanv. 2024
Micronutrition, Métabolisme & Immunité

COVID-19 vaccine strategies

Dr Amin Gasmi, Yuliya M. Semenova, Sàdaf Noor, Amine Nehaoua, Rafiaa Malek, Habib Malek, +1 co-auteurs

Publication scientifique évaluée par les pairs signée par Amin Gasmi, Yuliya M. Semenova, Sàdaf Noor, Amine Nehaoua, Rafiaa Malek, Habib Malek, Geir Bjørklund, parue dans Elsevier eBooks (2024). DOI:10.1016/b978-0-323-95648-2.00005-8

Current medicinal chemistryJanv. 2024
Micronutrition, Métabolisme & Immunité

An Update on Glutathione’s Biosynthesis, Metabolism, Functions, and Medicinal Purposes

Dr Amin Gasmi, Aniqa Nasreen, Larysa Lenchyk, Roman Lysiuk, Massimiliano Peana, Nataliya Shapovalova, +9 co-auteurs

Glutathione (GSH) has been the focus of increased scientific interest in the last decades. It plays a crucial role in all major physiological processes by supplying antioxidant defenses through participating in cellular redox reactions in…

The interdisciplinary journal of Discontinuity Nonlinearity and ComplexitySept. 2023
Micronutrition, Métabolisme & Immunité

Calculation Methods in Heart Rate Variability

Dr Amin Gasmi

Publication scientifique évaluée par les pairs signée par Amin Gasmi, parue dans The interdisciplinary journal of Discontinuity Nonlinearity and Complexity (2023). DOI:10.5890/dnc.2023.12.010

Current medicinal chemistryJanv. 2024
Micronutrition, Métabolisme & Immunité

Potential drugs in COVID-19 management

Dr Amin Gasmi, Sadaf Noor, Alain Menzel, Nataliia Khanyk, Yuliya Semenova, Roman Lysiuk, +5 co-auteurs

The SARS-CoV-2 virus first emerged in China in December 2019 and quickly spread worldwide. Despite the absence of a vaccination or authorized drug specifically developed to combat this infection, certain medications recommended for other…

Current pharmaceutical designFévr. 2023
Neuroprotection & Santé Cérébrale

Natural Compounds Used for Treating Hair Loss

Dr Amin Gasmi, Pavan Kumar Mujawdiya, Natalia Beley, Mariia Shanaida, Roman Lysiuk, Larysa Lenchyk, +7 co-auteurs

Hair loss or alopecia is a common dermatological condition affecting up to 2% of the world population. It is often caused by hereditary factors, such as male or female pattern baldness, but it can also result from various environmental fa…

Pharmaceuticals (Basel, Switzerland)Janv. 2023
Micronutrition, Métabolisme & Immunité

Pharmacological Treatments and Natural Biocompounds in Weight Management

Dr Amin Gasmi, Pavan Kumar Mujawdiya, Amine Nehaoua, Mariia Shanaida, Yuliya Semenova, Salva Piscopo, +5 co-auteurs

The obesity pandemic is one of society's most urgent public health concerns. One-third of the global adult population may fall under obese or overweight by 2025, suggesting a rising demand for medical care and an exorbitant cost of health…

Critical reviews in food science and nutritionJanv. 2024
Phytochimie & Composés Bioactifs

Anticancer activity of broccoli, its organosulfur and polyphenolic compounds

Dr Amin Gasmi, Asma Gasmi Benahmed, Mariia Shanaida, Salvatore Chirumbolo, Alain Menzel, Wajiha Anzar, +9 co-auteurs

The use of natural bioactive constituents from various food sources for anticancer purposes has become increasingly popular worldwide. Broccoli (Brassica oleracea var. italica) is on the top of the consumed vegetables by the masses. Its r…

Pharmaceuticals (Basel, Switzerland)Avr. 2023
Micronutrition, Métabolisme & Immunité

Natural Ingredients to Improve Immunity

Dr Amin Gasmi, Mariia Shanaida, Oleksandra Oleshchuk, Yuliya Semenova, Pavan Kumar Mujawdiya, Yana Ivankiv, +5 co-auteurs

Comprendre natural ingredients improveNatural ingredients improve : pharmaceuticals (Basel). 2023 Apr 1;16(4):528. doi: 10.3390/ph16040528. ABSTRACT The immune system protects the body from infectious agents such as bacteria, viruses, or…

Current medicinal chemistryJanv. 2024
Micronutrition, Métabolisme & Immunité

Traditional Chinese Medicine as the preventive and therapeutic remedy for COVID-19

Dr Amin Gasmi, Torsak Tippairote, Pavan Kumar Mujawdiya, Alain Menzel, Roman Lysiuk, Mariia Shanaida, +3 co-auteurs

The coronavirus disease 2019 (COVID-19) pandemic still has tremendous impacts on the global socio-economy and quality of living. The traditional Chinese Medicines (TCM) approach showed encouraging results during previous outbreaks of Seve…

Current medicinal chemistryJanv. 2024
Métaux lourds, Toxicologie & Épigénétique

Coenzyme Q10 for enhancing physical activity and extending the human life cycle

Geir Bjørklund, Yuliya Semenova, Dr Amin Gasmi, Neluwa-Liyanage Ruwan Indika, Ihor Hrynovets, Roman Lysiuk, +4 co-auteurs

BACKGROUND: Coenzyme Q (CoQ) is an enzyme family that plays a crucial role in maintaining the electron transport chain and antioxidant defense. CoQ10 is the most common form of CoQ in humans. A deficiency of CoQ10 occurs naturally with ag…

Current medicinal chemistryJanv. 2024
Neuroprotection & Santé Cérébrale

Sleep, Dietary Melatonin Supplementation, and COVID-19

Dr Amin Gasmi, Yuliya Semenova, Sadaf Noor, Asma Gasmi Benahmed, Geir Bjørklund

BACKGROUND: During the COVID-19 pandemic, people suffered from major mental health problems. These include stress, anxiety, and confusion about the existing situation of home confinement. Melatonin is a popular anti-inflammatory and antio…

Archives of Razi InstituteFévr. 2023
Microbiote & Axe Intestin-Cerveau

A Boolean Network Approach to Study the Mechanism Associated with Inflammatory Response Induced by Porphyromonas gingivalis

A Gasmi Benahmed, S Noor, A Menzel, Dr Amin Gasmi

Anaerobic Porphyromonas gingivalis is a rod-shaped bacterium and is a primary agent of periodontal inflammation and thus periodontitis. This bacterium disturbs the normal flora of the oral cavity and causes dysbiosis. Databases including…

Current medicinal chemistryJanv. 2024
Phytochimie & Composés Bioactifs

Berberine: Pharmacological Features in Health, Disease and Aging

Dr Amin Gasmi, Farah Asghar, Saba Zafar, Petro Oliinyk, Oksana Khavrona, Roman Lysiuk, +9 co-auteurs

Comprendre berberine pharmacological featuresBerberine pharmacological features : curr Med Chem. 2024;31(10):1214-1234. doi: 10.2174/0929867330666230207112539. ABSTRACT BACKGROUND: Berberine is the main active compound of different herbs…

Antibiotics (Basel, Switzerland)Déc. 2022
Phytochimie & Composés Bioactifs

Metabolic Conditions and Peri-Implantitis

Asma Gasmi Benahmed, Dr Amin Gasmi, Torsak Tippairote, Pavan Kumar Mujawdiya, Oleksandr Avdeev, Yurii Shanaida, +1 co-auteurs

Dental implants to replace lost teeth are a common dentistry practice nowadays. Titanium dental implants display a high success rate and improved safety profile. Nevertheless, there is an increasing peri-implantitis (PI), an inflammatory…

Molecules (Basel, Switzerland)Déc. 2022
Neuroprotection & Santé Cérébrale

Neurotransmitters Regulation and Food Intake: The Role of Dietary Sources in Neurotransmission

Dr Amin Gasmi, Aniqa Nasreen, Alain Menzel, Asma Gasmi Benahmed, Lyudmila Pivina, Sàdaf Noor, +3 co-auteurs

Comprendre neurotransmitters regulation foodNeurotransmitters regulation food : molecules. 2022 Dec 26;28(1):210. doi: 10.3390/molecules28010210. ABSTRACT Neurotransmitters (NTs) are biologically active chemicals, which mediate the electr…

Springer eBooksJanv. 2023
Micronutrition, Métabolisme & Immunité

Physical Activity and COVID-19 Vaccines

Dr Amin Gasmi, Amine Nehaoua, Sàdaf Noor, Pavan Kumar Mujawdiya, David Bilstrom

Publication scientifique évaluée par les pairs signée par Amin Gasmi, Amine Nehaoua, Sàdaf Noor, Pavan Kumar Mujawdiya, David Bilstrom, parue dans Springer eBooks (2023). DOI:10.1007/978-981-99-1802-7_5

Archives of Razi InstituteDéc. 2022
Micronutrition, Métabolisme & Immunité

Comparative Analysis of the Efficacies of the GeneXpert and Solid Culture Media Techniques in the Diagnosis of Mycobacterium Tuberculosis

Dr Amin Gasmi, Z Nadeem, J Iqbal, S Kausar, A Gasmi Benahmed, S Noor, F S Khan, +9 co-auteurs

Tuberculosis is one of the predominant infectious diseases causing significant deaths worldwide. Detection of Mycobacterium tuberculosis bacilli (MTB) using culture media was officially recognized by World Health Organization. However, th…

Molecules (Basel, Switzerland)Oct. 2022
Micronutrition, Métabolisme & Immunité

The Role of Astaxanthin as a Nutraceutical in Health and Age-Related Conditions

Geir Bjørklund, Dr Amin Gasmi, Larysa Lenchyk, Mariia Shanaida, Saba Zafar, Pavan Kumar Mujawdiya, +8 co-auteurs

The current review provides an up-to-date analysis of scientific data on astaxanthin (ASX) sources and experimental studies on its health benefits as a potent antioxidant in the aging process. ASX is a liposoluble carotenoid nutrient and…

Critical reviews in food science and nutritionJanv. 2024
Micronutrition, Métabolisme & Immunité

Coenzyme Q10 in aging and disease

Dr Amin Gasmi, Geir Bjørklund, Pavan Kumar Mujawdiya, Yuliya Semenova, Salva Piscopo, Massimiliano Peana

Comprendre coenzyme q10 agingCoenzyme q10 aging : crit Rev Food Sci Nutr. 2022 Oct 27:1-13. doi: 10.1080/10408398.2022.2137724. Online ahead of print. ABSTRACT Coenzyme Q10 (CoQ10) is an essential component of the electron transport chain…

NutrientsOct. 2022
Micronutrition, Métabolisme & Immunité

Combined Supplementation of Coenzyme Q10 and Other Nutrients in Specific Medical Conditions

Torsak Tippairote, Geir Bjørklund, Dr Amin Gasmi, Yuliya Semenova, Massimiliano Peana, Salvatore Chirumbolo, +1 co-auteurs

Comprendre supplement combined supplementationSupplement combined supplementation : nutrients. 2022 Oct 19;14(20):4383. doi: 10.3390/nu14204383. ABSTRACT Coenzyme Q10 (CoQ10) is a compound with a crucial role in mitochondrial bioenergetic…

Archives of Razi InstituteOct. 2022
Micronutrition, Métabolisme & Immunité

Increasing Efficacy of Covid-19 Vaccines by Lifestyle Interventions

Dr Amin Gasmi, P Kumar Mujawdiya, S Noor, S Piscopo, S Résimont, A Menzel

COVID-19 caused a serious threat to the world population as it spread worldwide rapidly. Existing medicines and vaccines could not cure and control this deadly disease. In this regard, several vaccines have been proposed and designed to c…

Archives of Razi InstituteOct. 2022
Microbiote & Axe Intestin-Cerveau

Porphyromonas Gingivalis in the Development of Periodontitis: Impact on Dysbiosis and Inflammation

A Gasmi Benahmed, P Kumar Mujawdiya, S Noor, Dr Amin Gasmi

Chronic periodontitis is an inflammatory disease of the dental plaque and affects the soft tissues supporting the tooth. It is one of the most practical oral health issues across the globe and adversely affects the quality of life. In a n…

Molecules (Basel, Switzerland)Sept. 2022
Phytochimie & Composés Bioactifs

Polyphenols in Metabolic Diseases

Dr Amin Gasmi, Pavan Kumar Mujawdiya, Sadaf Noor, Roman Lysiuk, Roman Darmohray, Salva Piscopo, +8 co-auteurs

Comprendre polyphenols metabolic diseasesPolyphenols metabolic diseases : molecules. 2022 Sep 23;27(19):6280. doi: 10.3390/molecules27196280. ABSTRACT Polyphenols (PPs) are a large group of phytochemicals containing phenolic rings with tw…

Pharmaceuticals (Basel, Switzerland)Août 2022
Phytochimie & Composés Bioactifs

Quercetin in the Prevention and Treatment of Coronavirus Infections: A Focus on SARS-CoV-2

Dr Amin Gasmi, Pavan Kumar Mujawdiya, Roman Lysiuk, Mariia Shanaida, Massimiliano Peana, Asma Gasmi Benahmed, +3 co-auteurs

Comprendre quercetin prevention treatmentQuercetin prevention treatment : pharmaceuticals (Basel). 2022 Aug 25;15(9):1049. doi: 10.3390/ph15091049. ABSTRACT The COVID-19 outbreak seems to be the most dangerous challenge of the third mille…

arXiv (Cornell University)Août 2022
Micronutrition, Métabolisme & Immunité

Nonlinear Dynamics in Complexity Quantification

Dr Amin Gasmi

Chaotic systems which are due to nonlinearity have attracted a great concern in the current world and chaotic models. Systems for a wide range of operation conditions have their application in almost all branches of engineering and scienc…

Critical reviews in food science and nutritionJanv. 2023
Microbiote & Axe Intestin-Cerveau

Gut microbiota in bariatric surgery

Dr Amin Gasmi, Geir Bjørklund, Pavan Kumar Mujawdiya, Yuliya Semenova, Alexandru Dosa, Salva Piscopo, +3 co-auteurs

Gut microbes share a symbiotic relationship with humans and perform several metabolic and physiological functions essential for human survival. It has been established in several scientific studies that obesity and other metabolic complic…

Critical reviews in food science and nutritionJanv. 2023
Micronutrition, Métabolisme & Immunité

Physical activity and obesity spectrum disorders in post-bariatric surgery patients: A systematic review and Meta-analysis

Dr Amin Gasmi, Boukelia Boukhmis, Geir Bjørklund, Ibrahim H Elkhidir, Yuliya Semenova, Alexandru Dosa, +4 co-auteurs

OBJECTIVES: This systematic review and meta-analysis is based on randomized controlled trials evaluating the effect of physical activity on weight loss in adults undergoing bariatric surgery. The study compared certain biomarkers for indi…

Critical reviews in food science and nutritionJanv. 2023
Micronutrition, Métabolisme & Immunité

Dietary supplements and bariatric surgery

Dr Amin Gasmi, Geir Bjørklund, Pavan Kumar Mujawdiya, Yuliya Semenova, Alexandru Dosa, Salva Piscopo, +3 co-auteurs

Bariatric surgery or weight loss surgery has been in practice for achieving significant weight loss in patients who have failed to achieve weight loss after pharmacological interventions. The rising cases of obesity are a triggering facto…

Clinical immunology (Orlando, Fla.)Avr. 2022
Micronutrition, Métabolisme & Immunité

A global survey in the developmental landscape of possible vaccination strategies for COVID-19

Dr Amin Gasmi, Shvetha Srinath, Maryam Dadar, Lyudmila Pivina, Alain Menzel, Asma Gasmi Benahmed, +2 co-auteurs

The development of COVID-19 vaccines was promptly regulated to ensure the best possible approach. By January 2022, 75 candidates reached preclinical evaluation in various animal models, 114 vaccines were in clinical trials on humans, and…

European journal of nutritionFévr. 2022
Micronutrition, Métabolisme & Immunité

Micronutrients deficiences in patients after bariatric surgery

Dr Amin Gasmi, Geir Bjørklund, Pavan Kumar Mujawdiya, Yuliya Semenova, Massimiliano Peana, Alexandru Dosa, +3 co-auteurs

Bariatric surgery is an effective option for managing obesity and has gained general acceptance among patients in recent years. Generally, despite the high caloric intake, a bad nutritional habit of obese people results in the deficiency…

Health and technologyJanv. 2022
Micronutrition, Métabolisme & Immunité

Improving safety in dental practices during the COVID-19 pandemic

Asma Gasmi Benahmed, Dr Amin Gasmi, Wajiha Anzar, Mehreen Arshad, Geir Bjørklund

Coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It originated from the Chinese city of Wuhan and very quickly became a challenging public health…

Critical reviews in food science and nutritionJanv. 2023
Micronutrition, Métabolisme & Immunité

Nutritional and surgical aspects in prostate disorders

Dr Amin Gasmi, Geir Bjørklund, Sadaf Noor, Yuliya Semenova, Alexandru Dosa, Joeri J Pen, +4 co-auteurs

Prostate disorders are commonplace in medicine, especially in older men, with prostatitis, benign prostatic hyperplasia, and prostate cancer being the most abundant pathologies. The complexity of this organ, however, turns treatment into…

HAL (Le Centre pour la Communication Scientifique Directe)Janv. 2022
Micronutrition, Métabolisme & Immunité

What is Fast Fourier Transform?

Dr Amin Gasmi

Historical background The history of the Fast Fourier Transform (FFT) is of an interesting nature. It began in the year 1805 when Carl Friedrich Gauss tried to calculate and determine the orbit of certain asteroids from sample locations w…

Journal of oral biosciencesMars 2022
Micronutrition, Métabolisme & Immunité

A review on natural teeth whitening

Asma Gasmi Benahmed, Dr Amin Gasmi, Alain Menzel, Ihor Hrynovets, Salvatore Chirumbolo, Mariia Shanaida, +4 co-auteurs

Comprendre review natural teethReview natural teeth : j Oral Biosci. 2022 Mar;64(1):49-58. doi: 10.1016/j.job.2021.12.002. Epub 2021 Dec 13. ABSTRACT BACKGROUND: Discoloration of teeth occurs for various reasons. Common ingredients like s…

Archives of Razi InstituteDéc. 2021
Micronutrition, Métabolisme & Immunité

Nutrients Interaction with the Immune System

S Noor, S Piscopo, Dr Amin Gasmi

This study described the interactions of different nutritional components with the immune system. A detailed search was carried out on Google Scholar and PubMed databases to find out the relevant research studies using different keywords,…

Critical reviews in food science and nutritionJanv. 2022
Microbiote & Axe Intestin-Cerveau

Phosphocalcic metabolism and the role of vitamin D, vitamin K2, and nattokinase supplementation

Dr Amin Gasmi, Geir Bjørklund, Massimiliano Peana, Pavan Kumar Mujawdiya, Lyudmila Pivina, Adrien Ongenae, +2 co-auteurs

Calcium is involved in bone metabolism, regulation of nerve signaling, and release of neurotransmitters. Phosphorus is a structural component of ATP, participates in metabolic energy regulation, and ensures stability to biological membran…

Clinical immunology (Orlando, Fla.)Mai 2021
Microbiote & Axe Intestin-Cerveau

The microbiota-mediated dietary and nutritional interventions for COVID-19

Dr Amin Gasmi, Torsak Tippairote, Pavan Kumar Mujawdiya, Massimiliano Peana, Alain Menzel, Maryam Dadar, +2 co-auteurs

Worldwide, scientists are looking for specific treatment for COVID-19. Apart from the antiviral approach, the interventions to support healthy immune responses to the virus are feasible through diet, nutrition, and lifestyle approaches. T…

Archives of toxicologyAvr. 2021
Micronutrition, Métabolisme & Immunité

Krebs cycle: activators, inhibitors and their roles in the modulation of carcinogenesis

Dr Amin Gasmi, Massimiliano Peana, Maria Arshad, Monica Butnariu, Alain Menzel, Geir Bjørklund

A fundamental metabolic feature of cancerous tissues is high glucose consumption. The rate of glucose consumption in a cancer cell can be 10-15 times higher than in normal cells. Isolation and cultivation of tumor cells in vitro highlight…

Biological trace element researchJanv. 2022
Neuroprotection & Santé Cérébrale

The Role of Diet and Supplementation of Natural Products in COVID-19 Prevention

Dr Amin Gasmi, Salvatore Chirumbolo, Massimiliano Peana, Sadaf Noor, Alain Menzel, Maryam Dadar, +1 co-auteurs

Recently, a discussion has begun on the global management strategy against COVID-19 based on the hypothesis that individuals' macro- and micronutrient status combined with antiviral drugs and herbs can be an ally against the infection. Th…

Applied microbiology and biotechnologyFévr. 2021
Micronutrition, Métabolisme & Immunité

Chloroquine and hydroxychloroquine in the treatment of COVID-19: the never-ending story

Dr Amin Gasmi, Massimiliano Peana, Sadaf Noor, Roman Lysiuk, Alain Menzel, Asma Gasmi Benahmed, +1 co-auteurs

The anti-malarial drugs chloroquine (CQ) and hydroxychloroquine (HCQ) have been suggested as promising agents against the new coronavirus SARS-CoV-2 that induces COVID-19 and as a possible therapy for shortening the duration of the viral…

Journal of oral biosciencesJuin 2021
Micronutrition, Métabolisme & Immunité

The role of sugar-rich diet and salivary proteins in dental plaque formation and oral health

Asma Gasmi Benahmed, Dr Amin Gasmi, Maryam Dadar, Maria Arshad, Geir Bjørklund

Comprendre role sugar-rich dietRole sugar-rich diet : j Oral Biosci. 2021 Jun;63(2):134-141. doi: 10.1016/j.job.2021.01.007. Epub 2021 Jan 23. ABSTRACT BACKGROUND: Dental plaque is a complex colorless film of bacteria that develops on the…

Springer Innovations in Communication and ComputingJanv. 2021
Micronutrition, Métabolisme & Immunité

Enabled IoT Applications for Covid-19

Dr Amin Gasmi

Publication scientifique évaluée par les pairs signée par Amin Gasmi, parue dans EAI/Springer Innovations in Communication and Computing (2021). DOI:10.1007/978-3-030-68936-0_15

Clinical immunology (Orlando, Fla.)Mars 2021
Neuroprotection & Santé Cérébrale

Interrelations between COVID-19 and other disorders

Dr Amin Gasmi, Massimiliano Peana, Lyudmila Pivina, Shvetha Srinath, Asma Gasmi Benahmed, Yuliya Semenova, +3 co-auteurs

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory tract virus that causes Coronavirus disease (COVID-19). The virus originated in Wuhan, China, in December 2019 and has spread across the globe to-date. The…

Molecular neurobiologyMars 2021
Neuroprotection & Santé Cérébrale

Neurological Involvements of SARS-CoV2 Infection

Dr Amin Gasmi, Torsak Tippairote, Pavan Kumar Mujawdiya, Asma Gasmi Benahmed, Alain Menzel, Maryam Dadar, +1 co-auteurs

COVID-19 is a pandemic viral infection caused by a novel coronavirus, SARS-CoV2, which is a global concern of the twenty-first century for its rapid spreading in a short period. Apart from its known acute respiratory involvements, the CNS…

Current medicinal chemistryJanv. 2021
Micronutrition, Métabolisme & Immunité

Biomarkers of Senescence during Aging as Possible Warnings to Use Preventive Measures

Dr Amin Gasmi, Salvatore Chirumbolo, Massimiliano Peana, Pavan Kumar Mujawdiya, Maryam Dadar, Alain Menzel, +1 co-auteurs

Human life expectancy is increasing significantly over time thanks to the improved possibility for people to take care of themselves and the higher availability of food, drugs, hygiene, services, and assistance. The increase in the averag…

Current medicinal chemistryJanv. 2021
Métaux lourds, Toxicologie & Épigénétique

Obesity and Insulin Resistance: Associations with Chronic Inflammation, Genetic and Epigenetic Factors

Dr Amin Gasmi, Sadaf Noor, Alain Menzel, Alexandru Doşa, Lyudmila Pivina, Geir Bjørklund

BACKGROUND: Obesity is known to be a multifactorial disease. In its pathogenesis, different factors such as chronic inflammation, oxidative stress, insulin resistance, genetic factors, environmental effects, vegetative disturbance, and un…

AnaerobeAoût 2021
Microbiote & Axe Intestin-Cerveau

Association between the gut and oral microbiome with obesity

Asma Gasmi Benahmed, Dr Amin Gasmi, Alexandru Doşa, Salvatore Chirumbolo, Pavan Kumar Mujawdiya, Jan Aaseth, +2 co-auteurs

Comprendre association between gutAssociation between gut : anaerobe. 2021 Aug;70:102248. doi: 10.1016/j.anaerobe.2020.102248. Epub 2020 Aug 14. ABSTRACT In recent decades, obesity has become one of the most common lifestyle-associated di…

Clinical immunology (Orlando, Fla.)Nov. 2020
Micronutrition, Métabolisme & Immunité

Micronutrients as immunomodulatory tools for COVID-19 management

Dr Amin Gasmi, Torsak Tippairote, Pavan Kumar Mujawdiya, Massimiliano Peana, Alain Menzel, Maryam Dadar, +2 co-auteurs

COVID-19 rapidly turned to a global pandemic posing lethal threats to overwhelming health care capabilities, despite its relatively low mortality rate. The clinical respiratory symptoms include dry cough, fever, anosmia, breathing difficu…

Current medicinal chemistryJanv. 2021
Microbiote & Axe Intestin-Cerveau

Relationship between Gut Microbiota, Gut Hyperpermeability and Obesity

Dr Amin Gasmi, Pavan Kumar Mujawdiya, Lyudmila Pivina, Alexandru Doşa, Yuliya Semenova, Asma Gasmi Benahmed, +1 co-auteurs

Comprendre relationship between gutRelationship between gut : curr Med Chem. 2021;28(4):827-839. doi: 10.2174/0929867327666200721160313. ABSTRACT Intestinal hyperpermeability is a complex metabolic process mediated by different pathways i…

Applied microbiology and biotechnologySept. 2020
Micronutrition, Métabolisme & Immunité

Health benefits of xylitol

Asma Gasmi Benahmed, Dr Amin Gasmi, Maria Arshad, Mariia Shanaida, Roman Lysiuk, Massimiliano Peana, +4 co-auteurs

Many diseases, including caries, chronic inflammatory diseases, diabetes, and obesity, are associated with uncontrolled sugar consumption. Artificial sweeteners are commonly used in food and pharmaceutical industries as sugar substitutes…

African journal of rheumatologyAvr. 2020
Micronutrition, Métabolisme & Immunité

Predictive factors for the progression of early inflammatory arthritis to rheumatoid arthritis

Dr Amin Gasmi, F. Rahal, Radia Chetouane, Sabrina Haid, S. Bencheikh, Bellabes K. Ait, Imen Megateli, +9 co-auteurs

Objective: To identify factors predicting the progression of Early Inflammatory Arthritis (EIA) to Rheumatoid Arthritis (RA). Design: This was a prospective longitudinal study. Methods: Inflammatory rheumatism that could not be classified…

Clinical immunology (Orlando, Fla.)Juin 2020
Micronutrition, Métabolisme & Immunité

Individual risk management strategy and potential therapeutic options for the COVID-19 pandemic

Dr Amin Gasmi, Sadaf Noor, Torsak Tippairote, Maryam Dadar, Alain Menzel, Geir Bjørklund

It is an ugly fact that a significant amount of the world's population will contract SARS-CoV-II infection with the current spreading. While a specific treatment is not yet coming soon, individual risk assessment and management strategies…

Applied microbiology and biotechnologyFévr. 2020
Micronutrition, Métabolisme & Immunité

Calanus oil in the treatment of obesity-related low-grade inflammation, insulin resistance, and atherosclerosis

Dr Amin Gasmi, Pavan Kumar Mujawdiya, Mariia Shanaida, Adrien Ongenae, Roman Lysiuk, Monica Daniela Doşa, +4 co-auteurs

Calanus oil (COil) is a natural product extracted from marine zooplankton Calanus finmarchicus found in the North Atlantic Ocean. This oil is rich in wax esters of polyunsaturated fatty acids (PUFAs) and has been projected as the best alt…

International Peer-Reviewed JournalFévr. 2017
Micronutrition, Métabolisme & Immunité

Sédentarité : mode de vie ou inactivité ?

Dr Amin Gasmi, et al.

Le mot sédentarité provient du latin "sedere" qui signifie "être assis". L'étude célèbre de Morris et al. en 1953 (1) sur la sédentarité des conducteurs de bus à Londres a montré que l'incidence des pathologies coronariennes était plus él…